B Positive is very much designed to function in a mode similar to Mom, where some episodes can be schtick-y and full of easy punchlines, but the show is still able to shift gears into emotional, borderline dramatic episodes.
What makes the sitcom stand out are all the comedy chops that Thomas Middleditch ("Silicon Valley") and Annaleigh Ashford ("Masters of Sex"), who wring laughs out of every scene they're in.
Shows like this tend to ripen with time, so that, even if the writing never substantially matures, the characters do; they get real, like Pinocchio. Whether it has time, only time will tell.
The B Positive pilot is decent enough as CBS sitcoms go. It doesn't show the promise of The Big Bang Theory pilot but it's not as bad as plenty of other CBS's past sitcoms.
It's about time that someone gave Tony-winning spitfire Annaleigh Ashford a lead role that takes full advantage of her madcap personality and offbeat comic timing... Ashford is warm, wacky, larger and weirder than life.
It has an admittedly odd premise and does fall into certain CBS sitcom pitfalls along the way, but it's redeemed by stars Thomas Middleditch and Annaleigh Ashford, who make a stellar comedic duo right away.
