The life of Agnes, a young miserable woman, who flees from her former cruel husband to a small motel, where she meets a young man and has an affair with him, but when they find bugs in the bed, everything changes.
This is a movie about the dangers of letting love rob you of your reason and cut you off from the world, and, bugs in the bloodstream or not, who hasn't been there?
Ashley Judd and Michael Shannon (who reprises his stage persona) never allow us to categorize the main characters as one-dimensional nut jobs but two emotionally fractured souls who retreat into paranoid delusion.