The series deals with a comic story that can happen to humans in the future. In this series, it appears that humans are able to 'upload' themselves into their preferred choice for the afterlife. One day, when Nathan meets his early death, Nura receives him in his version of Heaven in order to coexist with each other. Nathan is still out of life near his loved ones, while Nora is alive to survive working with Nathan in the sky.
As easy as it is to compare Upload to a program such as The Good Place ... Greg Daniels' romantic-comedy-cum-mystery is more a commentary on capitalism, a topic it tackles as successfully as it does ineffectually.