Completing the excitement and challenges where the first season stops that follows the struggles of doctors in the emergency room, where they race against time, in order to save the lives of people during the night shift. In this new season, Callahan struggles after the attack held against the hospital.
Emergencies are over the top in the best Grey's fashion - cars plow into wedding parties, a motorcycling couple are both impaled on a piece of rebar, breast implants turn out to be leaking bags of cocaine.