We go back through that historical series of the second season, when Lorenzo goes to Rome to ask Pope Paul to extend Medici bank loan from the papal tides. It may be difficult, as he was rejected at a time when the Bazi of the Roman Catholic Church rejected the adopted Medeche priest. On the other hand, it seems that Lorenzo's mother got Cardinal Orsini to count his decisive support if Lorenzo married his niece Clarisse at that time.
Critics Of "Medici: The Magnificent - Season 2 [Sub: Eng]"
Daily Telegraph (UK)
February 08, 2019
More hysterical than historical, chronological accuracy obviously goes out the stained glass window - the Medicis were apparently not quite as cat-walk ready as suggested here.