In an attempt to save the life of her husband and all people alike, Starla, a young beautiful and smart married woman, who lives in a small town, where they struggle against a meteor falls there and causes many damages, as it transforms people into monsters and zombies, the thing that leads her to fight against saving her husband who is infected by that plague.
Done with a knowing wink and a nod, Slither doesn't offer much in the way of scares, but makes up for it in laughs and decent banter and a number of well executed gross out moments.
The problem with making a smart horror parody -- and James Gunn's Slither is a smart horror parody -- is that it's kind of like doing a virtuoso performance of 'My Way.' The skill of execution tends to be eclipsed by the tedium of the material.