Replace may not be destined to be a massive crossover, but I suspect it'll be one shared often by horror fans as a "Have you seen this?" cult favorite.
Replace is a bloody cautionary tale about both the human condition and the inevitable reach of science. See it before you're too old to appreciate its warning.
merging the tradition of Countess Elizabeth Báthory with a more modern quasi-vampiric quest for eternal youth, and tragically tracing the double standards in our differing attitudes to the ageing of men and women.
Kira's decaying skin [as] figurative and literal metaphor on aging and vanity is enough to build from. Adding an amnesia subplot [is] a clichéd excuse to hide secrets.