This is the story of a energetic indigo girl Mary (Mckeena Grace) who is being raised by her single uncle Frank Adler (Chris Evans) in a coastal town in Florida, having their landlord and best friend Roberta (Octavia Spencer) always around. The plans of Mary's uncle to take her to a normal school life are frustrated when her school teacher pays attention at Mary's mathematical abilities which subsequently come to her formidable Grandmother Evelyn (Lindsay Duncan), whose plans for the seven-year-old girl threaten to separate her with her beloved uncle. Meanwhile Frank and Mary's school teacher Bonnie find themselves in the relationship.
The question at the movie's heart is: What is best for Mary? The answer Gifted chooses is predictable, but that doesn't stop the movie from messing with your tear ducts.